Sir David Jason will reprise his role of Granville for an Open All Hours Christmas special.
Lynda Baron and Maggie Ollerenshaw will also return as nurse Gladys Emmanuel and Mavis in the 30-minute one-off episode Still Open All Hours.
"I'm really excited to be bringing back Open All Hours," said Jason. "I am sure there is an audience out there who would like to see what Granville has been getting up to in the corner shop.
"It will be a great family show for Christmas, and a fitting tribute to the legacy of Arkwright."
Granville will be seen running the grocery store with his son, having inherited it from his uncle Albert Arkwright (Ronnie Barker).
Roy Clarke, who wrote the original series, will return for Still Open All Hours.
"This has been fun - a great opportunity to work with David Jason again and to suggest how things at that corner shop might look today," said Clarke.
BBC controller of UK comedy production Mark Freeland added that he hoped the special episode "will bring broad grins to lots and lots of faces at Christmas".
Open All Hours originally aired between 1973 and 1985, running for 26 episodes across four series.
