The horror sequel also saw off competition from X-Men: Apocalypse and Now You See Me 2 VIDEO
The Conjuring 2 has topped the US box office after taking $40m in its first week.
The horror sequel beat Warcraft to the top spot, which is new at 2 with $24m.
Meanwhile, Now You See Me 2 is new at 3 with £23m, while Teenage Mutant Ninja Turtles: Out of the Shadows is at 4 with $14.8m.
X-Men: Apocalypse is at 5 with $10m, Me Before You is at 6 with $9.2m, and The Angry Birds Movie is at 7 with $6.7m.
Elsewhere, Alice Through the Looking Glass is at 8 with $5.5m and Captain America: Civil War is at 9 with $4.3m.
Finally, The Jungle Book rounds out the top ten with $2.7m.
The top ten in full is as follows: 1. (-) The Conjuring 2 - $40, 350,000
2. (-)Warcraft - $24, 356,000
3. (-) Now You See Me 2 - $23,025,000
4. (1) Teenage Mutant Ninja Turtles: Out of the Shadows - $14,800,000
5. (2)X-Men: Apocalypse - $10,000,000
6. (3) Me Before You - $9,210,000
7. (5) The Angry Birds Movie - $6,700,000
8. (4) Alice Through the Looking Glass - $5,544,821
9. (6) Captain America: Civil War - $4,300,195
10. (9) The Jungle Book- $2,721,000