All these big wigs telling us how great the new vaccine is...

[dutchman]

Labelled as 'terrorist' by UK government for objecting to unvaccinated children being banned from school!

[rebbonk]

Nearly 1 in 3 COVID-19 Vaccine Recipients Suffered Neurological Side Effects: Study
The people included in the study suffered from headaches, tremors, muscle spasms, insomnia, sleepiness, vertigo, and difficulty in concentration.

Almost a third of individuals who received a COVID-19 vaccine suffered from neurological complications including tremors, insomnia, and muscle spasms, according to a recent study published in the journal Vaccines.

The study analyzed 19,096 people who received COVID-19 vaccines in Italy in July 2021, out of which 15,368 had taken the Pfizer vaccine, 2,077 had taken the Moderna version, and 1,651 took the AstraZeneca version.

While both Pfizer and Moderna are mRNA vaccines, AstraZeneca, being an adenovirus vaccine, uses a different mechanism to trigger the immune response.

The study found that about 31.2 percent of vaccinated individuals developed post-vaccination neurological complications, particularly among those injected with the AstraZeneca jab. Different vaccines had a different “neurological risk profile.”

The neurological risk profile of the AstraZeneca vaccine included headaches, tremors, muscle spasms, insomnia, and tinnitus, while the risk profile of the Moderna vaccine included sleepiness, vertigo, diplopia (double vision), paresthesia (a feeling of numbness or itching on the skin), taste and smell alterations, and dysphonia (hoarseness or loss of normal voice). None of the subjects were hospitalized or died.

As to Pfizer vaccines, researchers found “an increased risk” of cognitive fog or difficulty in concentration.

AstraZeneca Risks

More than 53 percent of individuals who took an AstraZeneca shot suffered from headaches, which usually lasted for one day. Over 13 percent developed tremors, which typically reverted after a day as well.

Insomnia was reported among 5.8 percent of AstraZeneca recipients. However, the study notes that researchers were unsure whether the individuals actually developed insomnia or had a “misperception of their sleep quality due to vaccination stress.”

Tinnitus was reported by 2.7 percent of the people who took AstraZeneca shots. Tinnitus is a condition in which an individual hears ringing or other noises which are not caused by an external sound.

All these health complications had a higher risk of occurring after taking the first dose of the vaccine.

The study speculated that complications related to the AstraZeneca vaccine are attributable to two factors. “Firstly, the nature of the vaccine, which is a modified adenovirus vector that results in significant and persistent systemic immune activation; secondly, individual vulnerability related to a predisposing biology.”

Moderna and Pfizer Risks

Sleepiness was found in 39.7 percent of those who took Moderna jabs, with the condition usually lasting for a week. It suggested that there “could be a strict relationship between the development of sleepiness and immune responses to vaccine/infection.”

The study cited a “fascinating hypothesis” which suggests that influenza vaccines may lead to “the selective immune-mediated destruction of orexin-producing neurons, which is T-cell-mediated neuronal damage, thus triggering narcolepsy.”

Narcolepsy is a condition in which the brain is unable to control the ability to sleep or stay awake.

“Considering that the same can occur for COVID-19 vaccines, future investigations monitoring the new-onset hypersomnia findings in vulnerable individuals are urgently needed.”

Hypersomnia is the inability to stay awake and alert during the daytime, even though the person may have had plenty of sleep during the night.

About 15.9 percent of people who received Moderna shots had vertigo, a sensation which makes the individual feel that they or their surrounding environment is moving or spinning. It typically lasted for a day.
Paresthesia—a feeling of numbness or itching on the skin for no apparent reason—was reported in 14.5 percent of Moderna vaccine recipients, which went away after a day.

Among the people who received a Moderna jab, 2.7 percent reported diplopia, also known as double vision, which also lasted for about a day. “Symptomatic people showed an increased risk to develop diplopia after the second dose, as if a reactivation of the immune response was necessary to trigger diplopia.”

Meanwhile, about 6.4 percent of Pfizer vaccine recipients reported suffering from cognitive fog, with the condition usually reversing in a week.

“Brain fog is a type of cognitive impairment that presents as a ‘foggy brain state’, including a lack of intellectual clarity, difficulty with concentration, mental fatigue and anxiety,” the study said.

“Hypotheses including systemic inflammation crossing the blood–brain barrier, neuroinflammation after viral infection leads and microglial activation are emerging as explanations of this phenomenon in COVID-19 patients. An alternative speculation is that symptomatic people may have a subclinical cognitive dysfunction before vaccination, and that vaccination is a trigger.”

Females Highly Affected

The study found that females faced an “increased risk of developing neurological complications” following COVID-19 vaccination. “Our findings are in line with those of a recent study that revealed that several factors, including the female sex, were associated with greater odds of adverse effects,” it said.

The researchers suggested that greater female susceptibility to the vaccines’ neurological complications may be due to “genetic and hormonal factors.”

Females have two X chromosomes while males have one X chromosome and one Y chromosome. As the X chromosome “contains the most prominent immune-related genes in the human genome,” it can also cause “stronger inflammatory immune responses,” the study said.

Moreover, a primary female sex steroid called estradiol triggers a specific immunity process to produce “antibodies against infections.”

The study also raised concerns about comorbidities. In medical parlance, comorbidity describes the existence of more than one disease or condition in a body at the same time, which may or may not interact with one another.

“The evidence that immune system dysfunctions (allergies/immunodeficiency disorders) are frequently reported in our symptomatic group is more than a chance occurrence,” researchers said.

Comorbidities were present in 47.6 percent of the AstraZeneca vaccine recipients, 38.8 percent of those who took Moderna jabs, and 41.5 percent of individuals who received Pfizer shots, the study said.

In the AstraZeneca group, both allergies and non-neurological diseases were reported. “A history of antitumoral and anticoagulant drugs was more frequent in this population,” the study said.

Among Moderna and Pfizer recipients, allergies were “more frequently” observed. While some people who took Moderna had a prior history of neurological diseases and transfusions as well as previous COVID-19 infection, those who received Pfizer vaccines had a history of immunodeficiency disorders.

Even though the study detailed neurological complications arising from COVID-19 vaccination, it admitted to certain limitations.

“Firstly, our results should be interpreted with caution because of a possible overestimation of neurological events resulting from the self-reported symptoms,” it said.

“Secondly, we evaluated the risks associated with the first and second doses of the vaccine; however, the data concerning the second dose were limited, thus representing a potential bias in the study.”

While admitting its limitations, the study concluded that “clinicians should be aware that several neurological complications may commonly occur after COVID-19 vaccines.”

“Caution should be used when administering COVID-19 vaccines to vulnerable people, such as to those who suffer from allergies,” the study stated. “We strongly believe that our findings are relevant for public health regarding the safety of vaccines in a large cohort.”

The Epoch Times reached out to Moderna, Pfizer, and AstraZeneca for comment.

Additional Neurological Findings

Cardiologist Dr. Peter McCullough wrote about the study discussing neurological effects following COVID shots in an article on Substack.

“A shocking 31.2 percent of respondents to this large dataset sustained neurologic injury after two injections with verified data in health registries,” he wrote. “Most of the risk estimates indicate the safety profile is unacceptable. It is alarming that all neurological societies to date still recommend COVID-19 vaccines and none have issued safety warnings on the products.”

Dr. McCullough explained that an excess risk of 20 percent or greater is considered "clinically important."

Multiple other studies have found evidence of COVID-19 vaccines being linked to neurological complications. Back in October 2021, a study published in the Neurological Sciences journal stated that the “most devastating neurological post-vaccination complication is cerebral venous sinus thrombosis (CVST).”

CVST occurs when a blood clot develops in the venous sinuses of the brain. This blocks the blood from draining out of the brain, eventually resulting in the blood leaking into brain tissues and forming a hemorrhage, according to Johns Hopkins Medicine.

The study found that CVST was “frequently reported in females of childbearing age,” generally among those who took an adenovector vaccine. Individuals who received mRNA vaccination were reported to have Bell’s palsy, in which facial muscles weaken or enter into paralysis.

A November 2022 study in Current Neurology and Neuroscience Reports made similar findings, stating that there is “a greater than expected occurrence of severe neurological adverse events."

Dr. McCullough cited this study in an article the following month.

“Because the vaccines contain lipid nanoparticles loaded with genetic material that code for the damaging Spike protein, each patient faces a Russian Roulette of whether or not the nervous system will be hemodynamically showered with the damaging vaccine particles,” he wrote.

Despite studies suggesting the risk of medical complications, some experts continue to advise people to get COVID-19 jabs. According to John Hopkins Medicine, both Pfizer and Moderna are “highly effective in preventing serious disease, hospitalization, and death from COVID-19.”

It recommended people to get a COVID-19 shot as “we believe that their benefits outweigh their risks," Johns Hopkins Medicine said.

According to a position statement from the American Academy of Neurology (AAN) issued in 2021, the organization recommended COVID-19 vaccine mandates for health care employees and supported vaccinations for children under the age of 12.

Source: https://www.theepochtimes.com/health/nearly-1-in-3-covid-19-vaccine-recipients-suffered-neurological-side-effects-study-5519532

[dutchman]

Oxford AstraZeneca Covid jab was ‘defective’, claims landmark legal case



The Oxford-AstraZeneca Covid-19 vaccine has been branded “defective” in a multi-million pound landmark legal action that will suggest claims over its efficacy were “vastly overstated”.

The pharmaceutical giant is being sued in the High Court in a test case by Jamie Scott, a father-of-two who suffered a significant permanent brain injury that has left him unable to work as a result of a blood clot after receiving the jab in April 2021. A second claim is being brought by the widower and two young children of 35-year-old Alpa Tailor, who died after having the jab made by AstraZeneca, the UK-based pharmaceutical giant.

The test cases could pave the way for as many as 80 damages claims worth an estimated £80 million over a new condition known as Vaccine-induced Immune Thrombocytopenia and Thrombosis (VITT) that was identified by specialists in the wake of the AstraZeneca Covid-19 vaccine rollout.

Independent studies show the AstraZeneca vaccine was incredibly effective in tackling the pandemic, saving more than six million lives globally in the first year of the rollout. Last year, the World Health Organisation said the vaccine was “safe and effective for all individuals aged 18 and above” and that the adverse effect that has prompted the legal action was “very rare”.

The vaccine, which was heralded at its launch by Boris Johnson as a “triumph for British science”, is no longer used in the UK. The Government recommends three other vaccines for its autumn booster programme.

In the months following the rollout, the potential serious side effect of the AstraZeneca jab was identified by scientists. Following this, it was recommend it no longer be given to the under-40s in the UK because the risk of receiving the jab outweighed the harm posed by Covid.

AstraZeneca last night told the Telegraph that patient safety was its “highest priority”, that its vaccine, called Vaxzevria, had “continuously been shown to have an acceptable safety profile”, and that regulators around the world “consistently state that the benefits of vaccination outweigh the risks of extremely rare potential side effects”.

It is understood AstraZeneca, in its legal response, denies causing Mr Scott’s injuries.

Official figures from the Medicines and Healthcare products Regulatory Agency (MHRA) show at least 81 deaths in the UK are suspected to have been linked to the adverse reaction that caused clotting in people who also had low blood platelets. In total, almost one in five people who suffered from the condition died as a result, according to the MHRA’s own figures.

Victims and their lawyers question the Government’s monitoring of the rollout and point out that while Germany suspended the vaccine’s use for the under 60s at the end of March 2021 over the risk of rare blood clots, the UK stopped giving it to under 30s on April 7 and took another month to ban it for the under 40s.

Official figures obtained under a Freedom of Information request show that out of 148 payouts made by the Government under the Vaccine Damage Payment Scheme, which provides compensation to those injured by vaccines or to bereaved next-of-kin, at least 144 went to recipients of the AstraZeneca vaccine. Fewer than five people under the scheme received vaccines other than AstraZeneca.

Families complain the amount paid out under the scheme – a fixed tax-free sum of £120,000 – is insufficient, prompting them to bring the legal cases in the High Court against AstraZeneca.

The claim is being brought by Mr Scott under the Consumer Protection Act 1987 and argues that the AstraZeneca vaccine was “defective” in that it was not as safe as individuals were entitled to expect.

Read more: https://www.telegraph.co.uk/news/2023/1 ... gniter-rhr

[rebbonk]

Oh dear, yet more 'expert' advice has proven to be inaccurate...

No proof face masks ever worked against Covid, claims UKHSA boss

There is no solid evidence masks have ever slowed the spread of Covid, England’s former deputy chief medical officer said today.

Professor Dame Jenny Harries, who now heads the UK’s Health Security Agency, said the evidence that covers reduce transmission is “uncertain” because it is difficult to separate their effect from other Covid restrictions.

She also told the UK Covid Inquiry that government advice on making a mask with two pieces of fabric was ‘ineffective’.

Research shows at least three are needed for even a small effect on the spread of viruses, Dame Jenny said.

Meanwhile, she warned that advice to the public to wear masks during the pandemic could even have given people a “false sense of security” that they could reduce their risk of becoming infected if they wore one while dealing with others interacted.

Source: (and further detail) https://nybreaking.com/no-proof-face-masks-ever-worked-against-covid-claims-ukhsa-boss-who-warns-they-may-have-even-had-opposite-effect-on-spread-through-false-sense-of-security/

[rebbonk]

The final batch of the Pfizer documentation is released. Well, well, who's surprised? - W*nkers!

Final Batch of Pfizer Documents Released by FDA 800 Days After COVID Vaccine Approval
Now, independent scientists and researchers can see everything the FDA saw when it made its decision that this vaccine was "safe and effective."

The FDA released the final batch of documents it relied upon in licensing Pfizer’s Comirnaty COVID-19 vaccine for ages 16 and up—more than 800 days after the agency approved the shot.

The documents are “finally in the hands of the public, where they belong,” the Informed Consent Action Network said in a press release. “Now, independent scientists and researchers can see everything FDA saw when it made its decision that this vaccine was ‘safe and effective.'”

The recent documents disclosed as part of a Freedom of Information Act (FOIA) lawsuit against the U.S. Food and Drug Administration (FDA) show the agency knew its safety monitoring system was “not sufficient” for assessing the risk of heart conditions associated with Pfizer’s COVID-19 vaccine when it licensed the company's “Comirnaty” vaccine.

Documents also reveal numerous manufacturing problems in Pfizer batches released to the public and show the FDA knew about a phenomenon known as vaccine-associated enhanced disease (VAED) in those vaccinated who experience breakthrough COVID-19.

FDA Knew Safety Monitoring System Was 'Not Sufficient'

Federal health agencies claim COVID-19 vaccines are part of the “most intensive vaccine safety monitoring effort in U.S. history,” with “continuous” and “robust” safety monitoring that helps ensure that the vaccine's benefits outweigh any risks. Yet the final documents released from Pfizer’s biologic product file reveal the agency knew its safety monitoring program was not sufficient to assess the serious risks of myocarditis and pericarditis associated with Pfizer’s COVID-19 vaccine.

An FDA memo in the 51,893 pages of disclosures specifically addressed the agency’s CBER Sentinel Initiative and its ability to evaluate the risk for myocarditis and pericarditis following COVID-19 vaccination. The Sentinel program is the FDA’s national electronic system used to monitor the “safety of its regulated products” and is a “major part” of the agency’s mission to “protect public health.”

The memo states:

“The CBER Sentinel Program is NOT sufficient to assess the serious risks of myocarditis and pericarditis, and subclinical myocarditis associated with COMIRNATY (BNT162b2) in lieu of PMR safety studies under FDAAA [Food and Drug Administration Amendments Act].

“At the time of BLA [Biologics License Application] approval, the data sources in the CBER Sentinel Program are not sufficient to identify the outcomes due to lack of sufficient power to assess the magnitude of risk in patients 12-30 years of age. In addition, CBER Sentinel Program is not sufficient to follow up cases for recovery status and long-term sequelae, or for identification and characterization of subclinical myocarditis cases.”

Cardiac Disorders Higher in Vaccine Trial Group

According to an Aug. 23, 2021, BLA Clinical Review Memorandum, there were more cardiac disorders in trial participants who received Pfizer’s COVID-19 vaccine compared to the placebo group and more instances of tachycardia in the younger vaccinated age group.

Cardiac conditions were reported as the cause of death in nine participants 25 to 128 days after having received at least one dose of Pfizer’s COVID-19 vaccine, including seven cases of cardiac arrest, one case of cardiovascular disease, and one case of congestive heart failure.

Five cardiac-related deaths in the placebo group occurred 15 to 81 days after having received a placebo, including two cases of myocardial infarction, one aortic rupture, and two cardiac arrests.

“Because COVID-19 mRNA and its Spike protein are found in the human heart at autopsy causing inflammation and heart damage, it is incontrovertible that the COVID-19 vaccines are cardiotoxic,” cardiologist Dr. Peter McCullough told The Epoch Times in an email.

“Younger individuals with healthy hearts take up more of the damaging vaccine into the cardiac tissue resulting in symptoms of chest pain, palpitations, fluctuations in blood pressure, dizziness, and sadly, some, end up with cardiac arrest either during exercise or in the early morning waking hours. At both time periods, an internal surge of adrenalin appears to be the trigger for the fatal arrhythmia in those with COVID-19 vaccine myocarditis,” he added.

Despite nearly double the number of reported cardiac events in vaccine recipients versus placebo recipients, the FDA concluded the deaths were “unlikely to be related to vaccination.”

“As a cardiologist, these serious adverse events are unacceptable,” Dr. McCullough said. “I have called for all COVID-19 vaccines to be removed from the market with an urgent push for research strategies to prevent cardiac death after injection.”

Vaccines Released Despite Manufacturing Issues

According to the Pfizer Andover Response to Form FDA 483 included in the released documents, numerous manufacturing issues and inadequacies in quality oversight were also identified. Several batches of COVID-19 vaccines were flagged for deviating from product quality standards, yet the affected batches were released to the public in various lots, the numbers of which were redacted.

In November 2021, whistleblower Brook Jackson, who worked as a regional director at testing sites by Pfizer contractor Ventavia, told the British Medical Journal that Pfizer's trial was riddled with issues. Ms. Jackson said the company “falsified data, unblinded patients, employed inadequately trained vaccinators, and was slow to follow up on adverse events reported in Pfizer’s pivotal phase III trial.”

Ms. Jackson, a trained clinical trial auditor with more than 15 years of experience in clinical research coordination and management, emailed a complaint to the FDA and was fired later that day. She subsequently filed a lawsuit against Ventavia and Pfizer, alleging Pfizer had defrauded the government while developing its COVID-19 vaccine.

FDA Acknowledges Vaccine-Associated Enhanced Disease

In its Pharmacovigilance Plan Review Memorandum, the FDA referenced a condition called “vaccine-associated enhanced disease.” According to the journal Vaccine, VAED is the modified presentation of a clinical infection affecting individuals exposed to the wild-type pathogen after having received a vaccine for the same pathogen.

In its memo, the FDA stated there are reported deaths in the Vaccine Adverse Event Reporting System (VAERS) in patients reported to be fully vaccinated. Although the agency said that passive surveillance and spontaneous adverse event reporting generally cannot be used to conclude vaccine effectiveness because of the lack of a control group, reporter bias, and underreporting, “severe manifestations and death from COVID-19” increase the possibility of developing VAED, which has “overlapping clinical manifestations with natural SARS-CoV-2 infection, making it difficult to differentiate VAED from severe COVID-19 disease in individual VAERS reports.”

The FDA said Pfizer was assessing the condition in its continuation of Phase 3 clinical studies and active surveillance studies. VAED has been observed in other vaccine trials involving the dengue virus, respiratory syncytial virus, and measles.

FDA Took Over 800 Days to Release Data

The Public Health and Medical Professionals for Transparency, a nonprofit consisting of public health and medical professionals, scientists, and journalists, filed a FOIA lawsuit against the FDA in September 2021 to force the release of hundreds of thousands of documents relied upon by the agency in licensing Pfizer’s COVID-19 vaccine for individuals age 16 and older.

Even though the FDA said in a news release it was committed to “ensuring full transparency, dialogue and efficiency” regarding COVID-19 vaccines and reiterated its commitment to full transparency when it licensed Pfizer's Comirnaty vaccine, they wanted 75 years to produce an estimated 451,000 documents at a rate of 500 pages per month. It previously estimated it had 329,000 pages of responsive records and wanted 55 years to release them to the public.

Attorney Aaron Siri, who filed the lawsuit on behalf of the group, said the federal government was shielding Pfizer from liability, gave it billions of dollars, and forced Americans to get vaccinated while preventing the safety and efficacy data supporting the licensure of Pfizer’s COVID-19 vaccine from being released until the year 2076. Yet it only took 108 days from when Pfizer started producing records to the agency for the FDA to license its vaccine.

Source: https://archive.ph/5kKIa

[rebbonk]

Research indicates what many of us suspected from day 1...

COVID-19 Vaccines Can Potentially Worsen Cancer: Review
Researchers found many factors within COVID-19 vaccinations that predisposed cancer patients towards a worsening of their condition.

COVID-19 vaccines can trigger genetic changes in cancer patients that could aid in the further development of the disease in such individuals, according to a recent peer-reviewed analysis.
The review, published in the Cureus medical journal on Dec. 17, looked at the relationship between COVID-19 vaccines and cancer. A review of multiple studies led the authors to conclude that certain COVID-19 vaccines may create an environment that predisposes some cancer patients, including survivors, to “cancer progression, recurrence, and/or metastasis.”

The conclusion was based on two factors. First is the “multi-hit hypothesis” of cancer, which suggests that cancer is the consequence of several genetic mutations.

The second is the “growing evidence and safety reports” in the Vaccine Adverse Effects Report System (VAERS), which suggested that some cancer patients who took COVID-19 vaccines saw their conditions worsen.

“In light of the above and because some of these concerns also apply to cancer patients infected with SARS-CoV-2, we encourage the scientific and medical community to urgently evaluate the impact of both COVID-19 and COVID-19 vaccination on cancer biology and tumor registries, adjusting public health recommendations accordingly,” the review said.

The review focused on mRNA vaccines, Pfizer/BioNTech and Moderna, and adenovirus-vectorized vaccines, Johnson & Johnson and Oxford/AstraZeneca, as these products were most widely used in global COVID-19 vaccination campaigns.

mRNA vaccines have the potential to trigger a set of biological mechanisms that could lead to the progression of cancer, it said.

These effects are attributed to factors like the “pro-inflammatory action” of lipid nanoparticles (LNPs) and tumor-causing effects of the vaccines’ antigens, namely the spike protein.

LNPs are nanoparticle drug delivery systems that can be used to deliver DNA and mRNA into a body. The spike protein, found on the surface of the COVID-19 virus, facilitates the entry of the virus into healthy cells.

The authors who wrote the review are Raquel Valdes Angues from the Oregon Health and Science University School of Medicine in Portland and Yolanda Perea Bustos from the education department in the Government of Catalonia, Barcelona, Spain. They declared “no financial support” from organizations that might have an interest in their work and no other relationships or activities that could have influenced the review.

The analysis outlined several genetic effects that COVID-19 vaccines could have on cancer cells and thereby potentially negatively impact the lives of patients suffering from the illness.

Lymphopenia

The review noted that COVID-19 vaccination has been associated with lymphopenia—a condition in which there is an abnormally low count of lymphocytes, a type of white blood cell that helps the immune system fight against foreign bacteria and viruses.

Clinical trials of the Pfizer and AstraZeneca vaccine described a “decrease in plasma lymphocytes 6-8 days post-vaccination in 45 percent-46 percent of participants.”

“Lymphopenia has long been associated with increased cancer incidence and risk of malignancy,” said the review. “Lymphocyte alterations are frequent in patients with cancer and strongly impact prognosis and survival.”

Given that lymphopenia contributes to creating an environment favorable to the progression of cancer, “extreme caution” must be observed when recommending COVID-19 to cancer patients—“especially those undergoing anticancer treatment.”

Spike Proteins

The spike protein present in COVID-19 coronaviruses has two key functional subunits—S1 and S2. S1 helps the virus in infecting human cells and has been found to affect the mechanism of cell growth.

Meanwhile, the spike protein has been shown to influence a mechanism that regulates several key cellular behaviors, specifically inflammatory responses and cellular growth. When activated in cancer cells, this specific mechanism promotes chemoresistance and proliferation. In a tumor microenvironment, it stimulates immune suppression.

As COVID-19 vaccines introduce spike proteins into the body, “it is hence imperative to monitor the mid-and long-term consequences” of such vaccination, the review stated.

Compromising Immunity

Researchers suggested that mRNA vaccines are “designed to deactivate” an individual’s innate immunity.

The innate immune system of mammals is stimulated through the activation of a class of proteins called Toll-like receptors (TLRs). TLRs are known to trigger several signaling pathways for the production of various cytokines that play an important role in many diseases, including cancer.

The signaling pathways involve IFN regulatory factors (IRFs) critical in several aspects of immune response. The review cited research showing that Pfizer COVID-19 vaccines “significantly decreased” the production of type I IFN and type II IFN.

TLRs are not only expressed in immune cells but also in tumor cells, in which they can either promote or inhibit malignancy. Type I IFN has also been found to be important in controlling the growth of tumors and in the response to anti-tumor therapies.

The review notes that the “exceedingly complicated” role of TLR and type I IFN responses in tumor biology “prompt caution” when using synthetic mRNAs for therapeutic applications.

Inflammatory

The lipid nanoparticles (LNP) used in the mRNA vaccines have been found to be “highly inflammatory” in mice, the review said, citing a report.

Injection of LNPs led to “rapid and robust activation of diverse inflammatory pathways” as well as the production of various inflammatory cytokines and chemokines in the mice. Cytokines and chemokines regulate responses to injuries and infections.

In the context of cancer, inflammation is conducive to the development of the disease and promotes all stages of tumorigenesis—the initial formation of a tumor in an individual.

“Around 15 percent-20 percent of all cancer cases are preceded by infection, chronic inflammation, or autoimmunity at the same tissue or organ site,” the review stated. “In such cases, cancer-promoting inflammation is induced and exists long before tumor formation.”

Such extrinsic inflammation—referring to inflammation caused by outside sources—can result in immunosuppression, where the immune system becomes temporarily dysfunctional. This immunosuppression can provide the environment for the development of tumors.

“Given that LNPs often accumulate in tumors, due to enhanced permeability and retention effect (EPR), protecting cancer cells from transformation-related stress stimuli, including inflammation …. is of paramount importance,” the authors wrote.

Genomic Integration

The review highlighted a study discussing the possibility that certain parts of the COVID-19 virus might undergo “genomic integration within infected cells.”

The study found copies of the virus in human cells and speculated that the same phenomenon could occur once human cells are exposed to COVID-19 mRNA vaccines.

Another study found that a “retrotransposon” called long interspersed nuclear element-1 (LINE-1) was affected following cellular exposure to the Pfizer COVID-19 mRNA vaccine. Retrotransposons are genetic elements that replicate and integrate the DNA into new sites in a genome.

The review speculated that the mRNA vaccine’s impact on LINE-1 might “enhance the risk of mutations in tumor suppressor genes and lead to sustained DNA damage in cells and tissues targeted by the vaccine.”

The researchers insisted that there is a “pressing need for clarity on the potential COVID-19- and COVID-19 vaccine-induced activation of LINE-1 and its repercussions in cancerous and/or precancerous cells with intrinsic high levels of LINE-1 expression.”

Tumor Suppression

An October 2020 study showed that the S2 subunit of the COVID-19 virus “strongly interacts” with tumor suppressor proteins p53 and BRCA1/2, said the review.

Proteins like p53 and BRCA1/2 act as a “major barrier” to tumor progression. The possibility that the virus’ spike protein can interact with tumor suppressor protein is critical since both mRNA and adenovirus-vectorized vaccine contain the “genetic material that instructs the host cells to express spike.”

Studies on the Pfizer vaccine have shown that it accumulates in various organs within 48 hours of vaccination. In addition, lipid nanoparticles “preferentially accumulate” in the tumor tissue rather than the healthy tissue.

Given these findings, the review suggested a detailed look into the potential interactions between S2 and tumor suppressor proteins p53 and BRCA1/2 in both COVID-19 patients and those who have received COVID-19 vaccination.

Such an analysis is necessary to determine if the interactions provide a “selective advantage” for cancer or precancerous cells, the researchers wrote.

Mutations to TP53, the gene that provides instructions for making p53, can lead to cancers of the breast, bone, soft tissue, and brain. Less frequent cancers include stomach cancer, leukemia, and colorectal cancer. Impaired BRCA1 activity is associated with cancers of the breast, ovaries, uterus, and prostate.

‘Dubious’ Vaccination Benefits

The researchers noted that they have shown COVID-19 spike protein-based vaccines to “have the potential to interact with tumor suppressor proteins, promote inflammation, activate oncogenic pathways, and disrupt the fine-tuning of the immune response.”

“These dysregulated mechanisms and signaling pathways underlie most types of cancer.” A more “balanced risk/benefit evaluation is urgently needed” regarding COVID-19 vaccination and people with or at high risk of cancer.

For people with poor immune responses, “the benefits of vaccination are dubious, and the cumulative risks of successive boosters are unknown.”

An area of concern is that the co-administration of anticancer treatments and COVID-19 vaccines could pave the way for “toxic effects.” The review cited an article that found that when cancer patients were given Pfizer’s COVID-19 vaccine, there was a “constant and variable increase of all COVID-19 vaccination side effects.”

“There is thus a concern that the simultaneous use of immunotherapy and COVID-19 vaccines boosts the body’s immune response, resulting in enhanced immune-related adverse events,” the researchers wrote.

The review stated that between Jan. 7, 2018, and July 2, 2022, there were approximately 13,000 cancer deaths per week in the United States, with peaks occurring in January 2021 and January 2022. While public health agencies have admitted a rise in cancer deaths, they have mostly attributed the excess deaths to the COVID-19 infection.

Even though cancer mortality peaks in 2021 and 2022 correlate with COVID-19 winter surges, “they also follow two major COVID-19 vaccination and booster campaigns,” the researchers pointed out.

“As noted earlier, both SARS-CoV-2 and SARS-CoV-2 spike protein-based vaccines promote the production of spike within human cells, which, in light of the above, might facilitate malignant transformation.”

The authors noted that even though many institutions and experts promote COVID-19 vaccines as safe and effective in patients with cancer, “these claims are unsupported.”

“Our suggestion is that individuals with cancer or a history of cancer should receive the genetic COVID-19 vaccines only if the benefits clearly outweigh any risks and after careful evaluation case by case,” said the review.

“Most importantly, there is the possibility that cancer risk is dose-dependent.” As such, only individuals who have taken multiple COVID-19 immunizations may be at higher risk of cancer malignancy.

“The success of the novel mRNA-based vaccines against COVID-19 has created a widespread interest in mRNA technology as a solution to some of the deadliest infectious diseases (i.e., malaria, tuberculosis, and HIV/AIDS) for which an effective and easily deployable vaccine is urgently needed,” the authors wrote.

However, “current safety concerns should be promptly addressed before mRNA-based nanomedicines further transform the way diseases are managed and prevented in the future.”

Source: https://www.theepochtimes.com/health/covid-19-vaccines-can-potentially-worsen-cancer-review-5552341

[dutchman]

We’re being censored, claim victims of AstraZeneca Covid vaccine



Victims who suffered life-changing injuries from the Oxford-AstraZeneca Covid vaccine say they have faced censorship on social media when trying to discuss their symptoms.

The Telegraph previously revealed the UK-based pharmaceutical giant is being sued in the High Court in a test case by a father-of-two who suffered a significant permanent brain injury as a result of a blood clot after receiving the jab in spring 2021.

A second claim is also being brought by the widower and two young children of a woman who died after having the jab.

Some who have experienced serious adverse reactions from the AstraZeneca vaccine, but who are not involved in the legal action, have been given “warnings” on social media websites such as Facebook when trying to talk to one another about their experiences.

They say they are being forced to “self censor” and speak in code to avoid having their support groups shut down.

In one instance, YouTube attempted to censor a video of testimony given by lawyers to the Covid Inquiry about vaccines, flagging the clip as a violation of its “medical misinformation policy”.

UK CV Family, a private Facebook group with 1.2k members for people left injured or bereaved from Covid vaccines, was started in November 2021 by Charlet Crichton after she suffered an adverse reaction from the AstraZeneca jab.

The 42 year-old, who was volunteering at a mass vaccination centre near her home in Folkestone, Kent, when she received her first vaccine, has since lost her sports therapy business and says she often spends weeks at a time bedbound.

“I set up the group because I was finding people online in the UK like me. And we felt we didn’t have anyone to talk to about it apart from each other,” Ms Crichton said.

UK CV Family is one of three vaccine bereaved groups to have been granted core-participant status in the Covid Inquiry, meaning they will be allowed to give evidence.

It describes itself as “not anti-vax” on its Facebook group, and asks members to “refrain from posting anything that suggests otherwise”.

Ms Crichton said: “We very quickly learned that we had to self censor, otherwise we’d be shut down.”

Account banned

Facebook blocked Ms Crichton from commenting at one stage “to prevent misuse” and there were occasions where her account was temporarily banned because her “activity didn’t follow our community standards”.

Ms Crichton claims breaches such as these came after she shared vaccine-related articles from legitimate sources and had conversations which used certain buzzwords, including “booster” and “vaccine”.

She also alleges that social media platforms “shadow banned” members who fell foul of the guidelines, a process which sees the algorithm hide some posts from others on the app.

“We are getting censored just because people are talking about their symptoms and trying to get peer support from people that do the same thing,” she said.

“It’s very, very difficult because we want to talk about what we’re going through. We need to talk about what we’re going through.”

Facebook said no content on the group had been removed, but did not comment on whether restrictions had been put in place on some members.

After two doses of the AstraZeneca vaccine, Ms Crichton claims she suffered from myocarditis, which went undiagnosed for several months and led to her developing fibrosis, or scarring of the heart.

The Medicines and Healthcare products Regulatory Agency (MHRA) said it had received several reports of myocarditis and pericarditis (heart inflammation) following Covid vaccination, including from people who have received the AstraZeneca jab.

She also now suffers from different arrhythmias, meaning her heart rate can suddenly go really fast, or drop severely low, at any random point in the day.

Her NHS record shows at least four logged events where medical professionals treated her for an “adverse reaction to SARS-CoV-2 vaccine”.

She has since lost her sports therapy business, which she ran for 13 years, and can no longer work. She has also spent more than £18,000 on private healthcare trying to get to the bottom of her symptoms.

Separately, it emerged that YouTube tried to censor videos of testimony given by lawyers to the Covid Inquiry about vaccines.

Stephen Bowie, a member of the Scottish Vaccine Injury Group (SVIG) – also a core participant in the Covid Inquiry – attempted to upload footage of a statement given in a hearing by Anna Morris KC, a lawyer representing those who have suffered injuries or bereavements from jabs, to his YouTube channel.

The platform flagged the clip, in which Ms Morris speaks about patients who died from blood clots and other side effects determined to have been caused by vaccines, as a violation of its “medical misinformation policy”.

Mr Bowie, who suffered a spinal stroke and blood clots after having the AstraZeneca vaccine, was told by YouTube: “We reviewed your content carefully, and have confirmed that it violates our medical misinformation policy.”

It added: “We know this is probably disappointing news, but it’s our job to make sure that YouTube is a safe place for all.”

YouTube has since allowed the video to be posted and admitted it sometimes makes “mistakes” when removing content.

Ms Morris KC told the inquiry: “Censorship is a very real issue for the vaccine injured and bereaved.

“Their support groups have been shut down by social media platforms and their experiences censored by the mainstream media.

Molly Kingsley, the co-founder of Us4Them, whose views on the vaccination of children were flagged by the Government’s Counter-Disinformation Unit, criticised YouTube for what she described as an “Orwellian” action.

“It should go without saying that for a social media platform to be flagging witness testimony given by a KC to the official UK Covid Inquiry is both sinister and utterly wrong,” she told The Telegraph.

[rebbonk]

Slightly off topic, but notice the similarities here to the Post Office scandal that has been televised?

Deny, demonise, deplatform and disconnect.

[dutchman]

Vinay Prasad, MD MPH; Physician & Professor
Hematologist/ Oncologist
Professor of Epidemiology, Biostatistics and Medicine, University of California San Francisco
Author of 450+ Peer Reviewed papers, 2 Books, 2 Podcasts, 100+ op-eds.

Annoyingly, there's either no link to the Austrian study mentioned in the video or it's possible YouTube removed it.

[rebbonk]

I have had little trust in the ONS for quite a while, this video casts doubt about other organisations that were once unimpeachable, but are now using deliberately 'naughty' tactics to exploit most people's ignorance of statistics!

Norman Fenton is a British mathematician and computer scientist. He is Professor of Risk Information Management in the School of Electronic Engineering and Computer Science at Queen Mary University of London.